According to research, the following conditions may benefit from this amazing medicinal weed.
The US Government is a fraud, because they know marijuana is a valuable medicine, yet they claim it has no medicinal value. In fact, the US Government, even though they put people into prison for marijuana, knows full well how valuable marijuana is as a medicine.
These hypocrites, in the US Government, have taken out a patent on medical marijuana.
And, Government has known of at least one medicinal use of marijuana since at least April 21, 1999, which is when they filed their patent for a medicinal use of marijuana.
So, the US Government will gladly put you in jail for possessing, or growing, a natural plant which they claim has no medicinal value, yet they themselves applied for, and received, a patent which claims otherwise. Which really says our politicians and bureaucrats are just hypocrites.
Among the claims made by the hypocritical US Government in their patent for medical marijuana are:
So, even the US Government knows marijuana is real medicine.
It's true, hypocrites run the world.
9/15/04 News Release
Source: Stanford University School of Medicine
STANFORD, Calif. - From the munchies to the giggles to paranoia, smoking marijuana causes widespread changes in the brain. Now researchers at Stanford University School of Medicine are a step closer to understanding how the drug's active ingredients - tetrahydrocannabinol and related compounds, called cannabinoids - may exert their effects.
David Prince, MD, the Edward F. and Irene Thiele Pimley Professor of Neurology and Neurological Sciences, and his colleagues found that a group of neurons that act as information gatekeepers in the brain's major information processing center, called the cerebral cortex, release cannabinoids that quiet their own activity. This form of self-inhibition is a novel way for neurons to regulate their own ability to send messages to their neighbors. Tetrahydrocannabinol from marijuana may work its brain-altering magic by binding to these same cells.
"Marijuana is a major drug of abuse with actions in the brain that aren't entirely known. Now we understand one piece of the puzzle," Prince said. The work of Prince and his colleagues John R. Huguenard, PhD, associate professor of neurology and neurological sciences, and Alberto Bacci, PhD, staff research associate, is published in the Sept. 16 issue of Nature .
The cells under scrutiny lie in the cerebral cortex. This region processes information from the eyes, ears, skin and other sense organs, regulates movement and performs complex functions such as those involved in thinking, learning and emotions. The cortex contains two major types of nerve cells: pyramidal neurons that excite both local and more distant neighbors, and inhibitory interneurons that act as local dimming switches, shutting down the activity of nearby brain cells. The inhibitory interneurons prevent the brain from taking in and responding to every thought, sight or sound it encounters. They also protect against runaway excitation such as that seen in epilepsy.
In previous work, other researchers had found that pyramidal cells manufacture and release cannabinoids that bind to a receptor on the membrane of interneurons. In this process, called retrograde signaling, the pyramidal cell does the equivalent of slipping its guardian interneuron some sleeping pills. It frees itself from inhibition by releasing cannabinoids that briefly decrease the interneuron's ability to release inhibitory molecules.
In contrast, Bacci and his colleagues found that interneurons can drug themselves when they get repetitively excited, triggering a self-inhibition process. The class of interneurons the researchers studied, the so-called "LTS cells" of the cerebral cortex, manufacture and release cannabinoids that bind to their own cannabinoid receptors and shut down their ability to signal other neurons. By shutting themselves off, the interneurons block their quieting action on the excitatory pyramidal cells - an effect that can last as long as 35 minutes, much longer than what had been seen with retrograde inhibition. Without the quieting effect, pyramidal cells signal more intensely, triggering a higher level of activity in circuits of the cortex.
Prince said it's too early to know exactly how marijuana binding to the cannabinoid receptor exerts its behavioral effects. However, because the interneurons inhibit cells that have such wide-ranging effects, it's no surprise that the drug alters how people perceive the world around them. "A loss of inhibition in pyramidal cells could produce changes in perception, in motor function and in everything the cerebral cortex does," he said.
The Stanford team hopes that by studying how these receptors work, researchers may learn how to make drugs that selectively bind and block subtypes of cannabinoid receptors on one type of cell but not another. This may be one way to harness the medically useful aspect of marijuana without causing brain-altering side effects.
According to Prince, such drugs could also be useful in treating epilepsy. Pyramidal cells are among those that fire out of control during a seizure. One reason these cells fire so rapidly may be that interneurons get shut down. A drug that blocks cannabinoid receptors on some types of inhibitory interneurons might allow them to continue quieting the pyramidal cells during periods of intense activity.
By Juanita King, The Muse (Memorial University of Newfoundland)
ST. JOHN'S, Nfld - Supporters of marijuana may finally have an excuse to smoke weed every day. A recent study in the Journal of Clinical Investigation suggests that smoking pot can make the brain grow.
Though most drugs inhibit the growth of new brain cells, injections of a synthetic cannibinoid have had the opposite effect in mice in a study performed at the University of Saskatchewan. Research on how drugs affect the brain has been critical to addiction treatment, particularly research on the hippocampus.
The hippocampus is an area of the brain essential to memory formation. It is unusual because it grows new neurons over a person's lifetime. Researchers believe these new cells help to improve memory and fight depression and mood disorders.
Many drugs -- heroin, cocaine, and the more common alcohol and nicotine - inhibit the growth of these new cells. It was thought that marijuana did the same thing, but this new research suggests otherwise.
Neuropsychiatrist Xia Zhang and a team of researchers study how marijuana-like drugs - known collectively as cannabinoids - act on the brain.
The team tested the effects of HU-210, a potent synthetic cannabinoid similar to a group of compounds found in marijuana. The synthetic version is about 100 times as powerful as THC, the high-inducing compound loved by recreational users.
The researchers found that rats treated with HU-210 on a regular basis showed neurogenesis - the growth of new brain cells in the hippocampus. A current hypothesis suggests depression may be triggered when the hippocampus grows insufficient numbers of new brain cells. If true, HU-210 could offer a treatment for such mood disorders by stimulating this growth.
Whether this is true for all cannabinoids remains unclear, as HU-210 is only one of many and the HU-210 in the study is highly purified.
"That does not mean that general use in healthy people is beneficial," said Memorial psychology professor William McKim. "We need to learn if this happens in humans, whether this is useful in healthy people, and whether THC causes it as well."
McKim warns that marijuana disrupts memory and cognition. "These effects can be long-lasting after heavy use," he said. "This makes it difficult to succeed academically if you use it excessively."
"Occasional light use probably does not have very serious consequences. [But] there is some evidence that marijuana smoke might cause cancer."
Still, the positive aspects of marijuana are becoming more plentiful as further research is done. McKim says it's not surprising that THC and compounds like it could have medicinal effects.
"Many have been identified," he said. "It stimulates appetite in people with AIDS, it is an analgesic, and blocks nausea in cancer patients undergoing chemotherapy. And it treats the symptoms of glaucoma."
The research group's next studies will examine the more unpleasant side of the drug.